Methotrexate Polyglutamates Exposure - Response Modeling in a Large Cohort of Rheumatoid Arthritis Patients Starting Methotrexate

Hebing, RCF; Bartelink, IH; Gosselt, HR; Heil, SG; de Rotte, MCFJ; de Jong, PHP; Nurmohamed, MT; de Jonge, R; Mathôt, RAA

Hebing, RCF (通讯作者),Amsterdam UMC Locat Reade, Amsterdam Rheumatol & Immunol Ctr, Amsterdam, Netherlands.

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2023; 114 (4): 893

Abstract

Methotrexate polyglutamates (MTX-PG) concentrations in red blood cells (RBCs) have been suggested as a biomarker of response in patients with rheumato......

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