Archaic humans have contributed to large-scale variation in modern human T cell receptor genes

Corcoran, M; Chernyshev, M; Mandolesi, M; Narang, S; Kaduk, M; Ye, KW; Sundling, C; Färnert, A; Kreslavsky, T; Bernhardsson, C; Larena, M; Jakobsson, M; Hedestam, GBK

Corcoran, M; Hedestam, GBK (通讯作者),Karolinska Inst, Dept Microbiol Tumor & Cell Biol, S-17177 Stockholm, Sweden.

IMMUNITY, 2023; 56 (3): 635

Abstract

Human T cell receptors (TCRs) are critical for mediating immune responses to pathogens and tumors and regulating self-antigen recognition. Yet, variat......

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