Pathogenic and Compensatory Mechanisms in Epidermis of Sphingomyelin Synthase 2-Deficient Mice

Sakai, S; Makino, A; Nishi, A; Ichikawa, T; Yamashita, T; Taniguchi, M; Tokudome, Y; Hirabayashi, Y; Akiyama, M; Crumrine, D; Uchida, Y; Elias, PM; Tsuchida, T; Hamanaka, S

Uchida, Y (corresponding author), Univ Calif San Francisco, Sch Med, Dept Dermatol, San Francisco, CA 94107 USA.; Uchida, Y (corresponding author), Vet Affairs Med Ctr, Northern Calif Inst Res & Educ, San Francisco, CA 94121 USA.

SKIN PHARMACOLOGY AND PHYSIOLOGY, 2021; 34 (5): 246

Abstract

Sphingomyelin (SM) is a constituent of cellular membranes, while ceramides (Cer) produced from SM on plasma membranes serve as a lipid mediator that r......

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