Clozapine increases macrophage migration inhibitory factor (MIF) expression via increasing histone acetylation of MIF promoter in astrocytes

Okazaki, S; Boku, S; Otsuka, I; Horai, T; Kimura, A; Shimmyo, N; Yamaki, N; Hishimoto, A

Boku, S (corresponding author), Kumamoto Univ, Fac Life Sci, Dept Neuropsychiat, Chuo Ku, Honjo 1-1-1, Kumamoto 8608556, Japan.

JOURNAL OF PSYCHIATRIC RESEARCH, 2021; 135 (): 237

Abstract

Macrophage migration inhibitory factor (MIF) is a pleiotmpic cytokine and promotes neurogenesis and neuro-protection in brains. In addition, MIF has b......

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