Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of gamma delta T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea

Schofield, L; Ioannidis, LJ; Karl, S; Robinson, LJ; Tan, QY; Poole, DP; Betuela, I; Hill, DL; Siba, PM; Hansen, DS; Mueller, I; Eriksson, EM

Eriksson, EM (reprint author), Walter & Eliza Hall Inst Med Res, Div Populat Hlth & Immun, Melbourne, Vic 3052, Australia.; Eriksson, EM (reprint author), Univ Melbourne, Dept Med Biol, Melbourne, Vic 3052, Australia.

BMC MEDICINE, 2017; 15 ( ):

Abstract

Background:gamma delta T cells are important for both protective immunity and immunopathogenesis during malaria infection. However, the immunological ......

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