Destabilizing heterochromatin by APOE mediates senescence

Zhao, HK; Ji, QZ; Wu, ZM; Wang, S; Ren, J; Yan, KW; Wang, ZH; Hu, JL; Chu, Q; Hu, HF; Cai, YS; Wang, QR; Huang, DY; Ji, ZJ; Li, JY; Belmonte, JCI; Song, MS; Zhang, WQ; Qu, J; Liu, GH

Qu, J (通讯作者),Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing, Peoples R China.;Qu, J (通讯作者),Univ Sci & Technol China, Hefei, Peoples R China.;Song, MS; Zhang, WQ; Qu, J; Liu, GH (通讯作者),Univ Chinese Acad Sci, Beijing, Peoples R China.;Song, MS; Liu, GH (通讯作者),Chinese Acad Sci, Inst Zool, State Key Lab Membrane Biol, Beijing, Peoples R China.;Song, MS; Zhang, WQ; Qu, J; Liu, GH (通讯作者),Chinese Acad Sci, Inst Stem Cell & Regenerat, Beijing, Peoples R China.;Song, MS; Zhan

NATURE AGING, 2022; 2 (4): 303

Abstract

Apolipoprotein E (APOE) is a component of lipoprotein particles that function in the homeostasis of cholesterol and other lipids. Although APOE is gen......

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