The blood-brain barrier and blood-tumour barrier in brain tumours and metastases

Arvanitis, CD; Ferraro, GB; Jain, RK

Arvanitis, CD (corresponding author), Georgia Inst Technol, Sch Mech Engn, Dept Biomed Engn, Atlanta, GA 30332 USA.; Jain, RK (corresponding author), Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiat Oncol, Edwin L Steele Labs, Boston, MA 02115 USA.

NATURE REVIEWS CANCER, 2020; 20 (1): 26

Abstract

For a blood-borne cancer therapeutic agent to be effective, it must cross the blood vessel wall to reach cancer cells in adequate quantities, and it m......

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