Prediction of Free Drug Absorption in Cyclodextrin Formulation by a Modified Physiologically Based Pharmacokinetic Model and Phase Solubility 3-D Surface Graph

Wang, W; Ouyang, DF

Ouyang, DF (corresponding author), Univ Macau, Inst Chinese Med Sci, Macau, Peoples R China.

PHARMACEUTICAL RESEARCH, 2021; 38 (7): 1157

Abstract

Purpose Cyclodextrin (CD) is commonly used to enhance the solubility of oral drugs. However, with the increase of CD concentrations, the fraction of f......

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