Dual role of sprouty2 as an inhibitor of RAS/ERK-driven proliferation and a promoter of cancer invasion in KRAS wild-type colorectal cancer

Lee, CT; Chu, CA; Wang, YM; Wang, YW; Chen, YL; Ho, CL; Yeh, YM; Lin, PC; Lin, BW; Chen, PC; Chen, SH; Chan, RH; Chang, C; Chow, NH

Chow, NH (通讯作者)，Natl Cheng Kung Univ, Natl Cheng Kung Univ Hosp, Coll Med, Dept Pathol, 138 Sheng Li Rd, Tainan 704302, Taiwan.

MOLECULAR CARCINOGENESIS, 2023; 62 (7): 951

Abstract

Sprouty2 (SPRY2) is known to inhibit the RAS/MAPK/ERK pathway, and is a potential study target for cancer. The effect of SPRY2 in colorectal cancer (C......

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