Insulin induces insulin receptor degradation in the liver through EphB4

Liu, XF; Wang, K; Hou, SC; Jiang, Q; Ma, CX; Zhao, QJ; Kong, LJ; Chen, JW; Wang, ZH; Zhang, HB; Yuan, T; Li, YX; Huan, Y; Shen, ZF; Hu, ZW; Huang, ZF; Cui, B; Li, PP

Li, PP (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing, Peoples R China.;Li, PP (通讯作者)，Chinese Acad Med Sci, Diabet Res Ctr, Beijing, Peoples R China.;Li, PP (通讯作者)，CAMS Key Lab Mol Mech & Target Discovery Metab Di, Beijing, Peoples R China.

NATURE METABOLISM, 2022; 4 (9): 1202

Abstract

The tyrosine kinase receptor EphB4 is shown to interact with the insulin receptor to facilitate its endocytosis and degradation, thereby decreasing in......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索