The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4+ memory T cells

Shepherd, FR; Davies, K; Miners, KL; Llewellyn-Lacey, S; Kollnberger, S; Redman, JE; Grant, MM; Ladell, K; Price, DA; McLaren, JE

McLaren, JE (通讯作者),Cardiff Univ, Sch Med, Div Infect & Immun, Cardiff, Wales.

COMMUNICATIONS BIOLOGY, 2023; 6 (1):

Abstract

Severe bacterial or viral infections can induce a state of immune hyperactivation that can culminate in a potentially lethal cytokine storm. The class......

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