PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates

Mathavarajah, S; Vergunst, KL; Habib, EB; Williams, SK; He, RY; Maliougina, M; Park, M; Salsman, J; Roy, S; Braasch, I; Roger, AJ; Langelaan, DN; Dellaire, G

Dellaire, G (通讯作者),Dalhousie Univ, Fac Med, Dept Pathol, Halifax, NS, Canada.;Langelaan, DN; Dellaire, G (通讯作者),Dalhousie Univ, Fac Med, Dept Biochem & Mol Biol, Halifax, NS, Canada.

NUCLEIC ACIDS RESEARCH, 2023; 51 (7): 3185

Abstract

We have uncovered a role for the promyelocytic leukemia (PML) gene and novel PML-like DEDDh exonucleases in the maintenance of genome stability throug......

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