Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules

Papadaki, GF; Ani, O; Florio, TJ; Young, MC; Danon, JN; Sun, Y; Dersh, D; Sgourakis, NG

Sgourakis, NG (通讯作者)，Childrens Hosp Philadelphia, Ctr Computat & Genom Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA.;Sgourakis, NG (通讯作者)，Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USA.

FRONTIERS IN IMMUNOLOGY, 2023; 14 ():

Abstract

Major Histocompatibility Complex class I (MHC-I) molecules display self, viral or aberrant epitopic peptides to T cell receptors (TCRs), which employ ......

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