Antibody-Drug Conjugates: Pharmacokinetic/Pharmacodynamic Modeling, Preclinical Characterization, Clinical Studies, and Lessons Learned

Hedrich, WD; Fandy, TE; Ashour, HM; Wang, HB; Hassan, HE

Hassan, HE (reprint author), Univ Maryland, Sch Pharm, Dept Pharmaceut Sci, Pharmacokinet & Biopharmaceut Lab, Rm N525,20 N Pine St, Baltimore, MD 21201 USA.; Hassan, HE (reprint author), Helwan Univ, Dept Pharmaceut & Ind Pharm, Fac Pharm, Cairo, Egypt.

CLINICAL PHARMACOKINETICS, 2018; 57 (6): 687

Abstract

Antibody-drug conjugates are an emerging class of biopharmaceuticals changing the landscape of targeted chemotherapy. These conjugates combine the tar......

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