Phosphoglycerate mutase 1 (PGAM1) overexpression promotes radio- and chemoresistance in gliomas by activating the DNA damage response

Johannessen, TCA; Mukherjee, J

Mukherjee, J (corresponding author), Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94158 USA.

MOLECULAR & CELLULAR ONCOLOGY, 2021; 8 (2):

Abstract

The glycolytic enzyme PGAM1 is overexpressed in gliomas where it efficiently facilitates the repair of DNA damage. Mechanistically, PGAM1 prevents ina......

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