An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis

Hards, K; Cheung, CY; Waller, N; Adolph, C; Keighley, L; Tee, ZS; Harold, LK; Menorca, A; Bujaroski, RS; Buckley, BJ; Tyndall, JDA; McNeil, MB; Rhee, KY; Opel-Reading, HK; Krause, K; Preiss, L; Langer, JD; Meier, T; Hasenoehrl, EJ; Berney, M; Kelso, MJ; Cook, GM

Cook, GM (通讯作者),Univ Otago, Dept Microbiol & Immunol, Dunedin, New Zealand.;Cook, GM (通讯作者),Univ Otago, Maurice Wilkins Ctr Mol Biodiscovery, Dunedin, New Zealand.;Kelso, MJ (通讯作者),Univ Wollongong, Mol Horizons, Wollongong, NSW, Australia.;Kelso, MJ (通讯作者),Univ Wollongong, Sch Chem & Mol Biosci, Wollongong, NSW, Australia.;Kelso, MJ (通讯作者),Illawarra Hlth & Med Res Inst, Wollongong, NSW, Australia.

COMMUNICATIONS BIOLOGY, 2022; 5 (1):

Abstract

Increasing antimicrobial resistance compels the search for next-generation inhibitors with differing or multiple molecular targets. In this regard, en......

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