JAK/STAT disruption induces immuno-deficiency: Rationale for the development of JAK inhibitors as immunosuppressive drugs

Cornez, I; Yajnanarayana, SP; Wolf, AM; Wolf, D

Wolf, D (reprint author), Univ Clin Bonn, Dept Med Clin Oncol Hematol Immunoncol & Rheumato, Sigmund Freud Str 25, D-53127 Bonn, Germany.

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2017; 451 (C): 88

Abstract

Cytokines are mediating immune cells responses through the activation of the JAK/STAT signaling pathway. Being critical for immune cells, a defective ......

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