Endocytosis of the thrombopoietin receptor Mpl regulates megakaryocyte and erythroid maturation in mice

Eaton, N; Boyd, EK; Biswas, R; Lee-Sundlov, MM; Dlugi, TA; Ramsey, HE; Zheng, SK; Burns, RT; Sola-Visner, MC; Hoffmeister, KM; Falet, H

Falet, H (通讯作者),Versiti Blood Res Inst, Translat Glyc Ctr, Milwaukee, WI 53226 USA.;Falet, H (通讯作者),Med Coll Wisconsin, Dept Cell Biol Neurobiol & Anat, Milwaukee, WI 53226 USA.

FRONTIERS IN ONCOLOGY, 2022; 12 ():

Abstract

Dnm2(fl/fl) Pf4-Cre (Dnm2(Plt-/-)) mice lacking the endocytic GTPase dynamin 2 (DNM2) in platelets and megakaryocytes (MKs) develop hallmarks of myelo......

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