SIRT3-mediated deacetylation protects inner hair cell synapses in a H2O2-induced oxidative stress model in vitro

Zhao, CL; Liang, WQ; Yang, ZJ; Chen, ZR; Du, ZD; Gong, SS

Du, ZD; Gong, SS (通讯作者)，Capital Med Univ, Beijing Friendship Hosp, Dept Otolaryngol Head & Neck Surg, Beijing 100050, Peoples R China.;Gong, SS (通讯作者)，Capital Med Univ, Beijing Friendship Hosp, Dept Otolaryngol Head & Neck Surg, 95 Yongan Rd, Beijing 100050, Peoples R China.

EXPERIMENTAL CELL RESEARCH, 2022; 418 (2):

Abstract

Oxidative stress is considered a driving event in the damage to inner hair cell (IHC) synapses. Mitochondrial deacetylase sirtuin 3 (SIRT3) is an impo......

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