The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

Dhagat, U; Hercus, TR; Broughton, SE; Nero, TL; Shing, KSCT; Barry, EF; Thomson, CA; Bryson, S; Pai, EF; McClure, BJ; Schrader, JW; Lopez, AF; Parker, MW

Parker, MW (reprint author), Australian Canc Res Fdn Rational Drug Discovery C, St Vincents Inst Med Res, Fitzroy, Vic, Australia.; Lopez, AF (reprint author), SA Pathol, Ctr Canc Biol, Adelaide, SA, Australia.; Lopez, AF (reprint author), Univ South Aust

MABS, 2018; 10 (7): 1018

Abstract

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor that can stimulate a variety of cells, but its overexpressi......

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