Synthesis and biological evaluation of Vinpocetine derivatives

Pan, BW; Shi, Y; Li, WC; Wang, Q; Pan, M; Wu, Q; Fu, HZ

Fu, HZ (corresponding author), Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020; 30 (2):

Abstract

A new series of Vinpocetine derivatives were synthesized and evaluated for their inhibitory activity on PDE1A in vitro. Seven compounds with higher in......

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