A clinical pharmacokinetic drug-drug interaction study between dextromethorphan and emvododstat, a potent anti-SARS-CoV-2 dihydroorotate dehydrogenase inhibitor

Morton, TL; Laskin, OL; Kaushik, D; Lee, LCY; Ma, JY; Bar, CM; Kristensen, A; O'Keefe, K; Golden, L; Klein, M; Kong, RA

Kong, RA (通讯作者),PTC Therapeut, 100 Corp Court, South Plainfield, NJ 07080 USA.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (8): 1073

Abstract

PurposeA therapeutic agent that targets both viral replication and the hyper-reactive immune response would offer a highly desirable treatment for sev......

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