BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms

Singh, A; Busacca, S; Gaba, A; Sheaff, M; Poile, C; Nakas, A; Dzialo, J; Bzura, A; Dawson, AG; Fennell, DA; Fry, AM

Fry, AM (通讯作者),Univ Leicester, Dept Mol & Cell Biol, Lancaster Rd, Leicester LE1 9HN, England.

ONCOGENE, 2023; 42 (8): 572

Abstract

The tumour suppressor BRCA1-associated protein 1 (BAP1) is the most frequently mutated cancer gene in mesothelioma. Here we report novel functions for......

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