MEK inhibitor enhanced the antitumor effect of oxaliplatin and 5-fluorouracil in MEK1 Q56P-mutant colorectal cancer cells

Jing, CW; Li, HZ; Du, YY; Cao, HX; Liu, SW; Wang, Z; Ma, R; Feng, JF; Wu, JZ

Wu, JZ (reprint author), Nanjing Med Univ, Affiliated Canc Hosp, Clin Canc Res Ctr, Jiangsu Canc Hosp, 42 Baiziting Rd, Nanjing 210009, Jiangsu, Peoples R China.; Feng, JF; Wu, JZ (reprint author), Nanjing Med Univ, Affiliated Canc Hosp, Jiangsu Inst Canc

MOLECULAR MEDICINE REPORTS, 2019; 19 (2): 1092

Abstract

Mitogen-activated protein kinase kinase (MEK) small molecule inhibitors have been investigated in preclinical or clinical trials for the treatment of ......

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