mTOR masters monocyte development in bone marrow by decreasing the inhibition of STAT5 on IRF8

Zhao, Y; Shen, XF; Na, N; Chu, ZL; Su, HT; Chao, SS; Shi, L; Xu, YA; Zhang, LF; Shi, BY; Zhao, Y

Zhang, LF (reprint author), Minist Hlth, Key Lab Human Dis Comparat Med, Pan Jia Yuan Nan Li 5, Beijing 100021, Peoples R China.; Zhang, LF (reprint author), Chinese Acad Med Sci, Inst Lab Anim Sci, Pan Jia Yuan Nan Li 5, Beijing 100021, Peoples R China.;

BLOOD, 2018; 131 (14): 1587

Abstract

Monocytes and macrophages play a key role in defending pathogens, removing the dead cells or cell debris, and wound healing. The mammalian target of r......

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