Durable blockade of PD-1 signaling links preclinical efficacy of sintilimab to its clinical benefit

Wang, J; Fei, KK; Jing, H; Wu, ZH; Wu, WW; Zhou, SX; Ni, HQ; Chen, BL; Xiong, Y; Liu, YP; Peng, B; Yu, DC; Jiang, HP; Liu, JJ

Jiang, HP (reprint author), Zhejiang Univ, Coll Med, Affiliated Hosp 1, Dept Med Oncol, 79 Qingchun Rd, Hangzhou 310003, Zhejiang, Peoples R China.; Liu, JJ (reprint author), Innovent Biol Suzhou Co, 168 Dongping St,Suzhou Ind Pk, Suzhou 215123, Jiangsu,

MABS, 2019; 11 (8): 1443

Abstract

Blockade of immune checkpoint pathways by programmed cell death protein 1 (PD-1) antibodies has demonstrated broad clinical efficacy against a variety......

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