Loss of Mst1/2 activity promotes non-mitotic hair cell generation in the neonatal organ of Corti

Lu, XL; Yu, HQ; Ma, JY; Wang, KK; Guo, L; Zhang, YP; Li, BA; Zhao, ZH; Li, HW; Sun, S

Yu, HQ; Li, HW; Sun, S (通讯作者)，Fudan Univ, NHC Key Lab Hearing Med, State Key Lab Med Neurobiol, Eye & ENT Hosp,ENT Inst, Shanghai 200031, Peoples R China.;Yu, HQ; Li, HW; Sun, S (通讯作者)，Fudan Univ, NHC Key Lab Hearing Med, State Key Lab Med Neurobiol, Eye & ENT Hosp,Dept Otorhinolaryngol, Shanghai 200031, Peoples R China.;Yu, HQ; Li, HW; Sun, S (通讯作者)，Fudan Univ, MOE Frontiers Ctr Brain Sci, NHC Key Lab Hearing Med, Shanghai 200031, Peoples R China.;Li, HW (通讯作者)，Fudan Univ, Inst Biomed Sci, Shan

NPJ REGENERATIVE MEDICINE, 2022; 7 (1):

Abstract

Mammalian sensory hair cells (HCs) have limited capacity for regeneration, which leads to permanent hearing loss after HC death. Here, we used in vitr......

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