Conformational Preference of 2 '-Fluoro-Substituted Acetophenone Derivatives Revealed by Through-Space H-1-F-19 and C-13-F-19 Spin-Spin Couplings

Otake, C; Namba, T; Tabata, H; Makino, K; Hirano, K; Oshitari, T; Natsugari, H; Kusumi, T; Takahashi, H

Takahashi, H (corresponding author), Tokyo Univ Sci, Fac Pharmaceut Sci, Noda, Chiba 2788510, Japan.

JOURNAL OF ORGANIC CHEMISTRY, 2021; 86 (6): 4638

Abstract

The conformational properties of 2'-fluoro-substituted acetophenone derivatives were elucidated based on H-alpha-F and C-alpha-F through-space spin-sp......

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