Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex

Li, SS; Xie, T; Liu, P; Wang, L; Gong, X

Gong, X (corresponding author), Southern Univ Sci & Technol, Dept Biol, Shenzhen, Guangdong, Peoples R China.

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2021; 28 (3):

Abstract

Human serine palmitoyltransferase (SPT) complex catalyzes the initial and rate-limiting step in the de novo biosynthesis of all sphingolipids. ORMDLs ......

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