17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes

Bowles, KR; Pugh, DA; Liu, YY; Patel, T; Renton, AE; Bandres-Ciga, S; Gan-Or, Z; Heutink, P; Siitonen, A; Bertelsen, S; Cherry, JD; Karch, CM; Frucht, SJ; Kopell, BH; Peter, I; Park, YJ; Charney, A; Raj, T; Crary, JF; Goate, AM

Goate, AM (通讯作者)，Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, New York, NY 10029 USA.;Goate, AM (通讯作者)，Icahn Sch Med Mt Sinai, Ronald M Loeb Ctr Alzheimers Dis, New York, NY 10029 USA.;Goate, AM (通讯作者)，Icahn Sch Med Mt Sinai, Icahn Genom Inst, New York, NY 10029 USA.;Goate, AM (通讯作者)，Icahn Sch Med Mt Sinai, Estelle & Daniel Maggin Dept Neurol, New York, NY 10029 USA.

MOLECULAR NEURODEGENERATION, 2022; 17 (1):

Abstract

Background Parkinson's disease (PD) is genetically associated with the H1 haplotype of the MAPT 17q.21.31 locus, although the causal gene and variants......

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