Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors

Kutil, Z; Mikesova, J; Zessin, M; Meleshin, M; Novakova, Z; Alquicer, G; Kozikowski, A; Sippl, W; Barinka, C; Schutkowski, M

Barinka, C (reprint author), Czech Acad Sci, Inst Biotechnol, BIOCEV, Prumyslova 595, Vestec 25250, Czech Republic.; Schutkowski, M (reprint author), Martin Luther Univ Halle Wittenberg, Charles Tanford Prot Ctr, Inst Biochem & Biotechnol, Dept Enzymol, K

ACS OMEGA, 2019; 4 (22): 19895

Abstract

Histone deacetylase 11 (HDAC11) preferentially removes fatty acid residues from lysine side chains in a peptide or protein environment. Here, we repor......

Full Text Link