Linear ubiquitination of cFLIP induced by LUBAC contributes to TNF-induced apoptosis

Tang, Y; Joo, D; Liu, GN; Tu, HL; You, J; Jin, JP; Zhao, XQ; Hung, MC; Lin, X

Lin, X (reprint author), Tsinghua Univ, Sch Med, Inst Immunol, Beijing 100084, Peoples R China.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2018; 293 (52): 20062

Abstract

The linear ubiquitin chain assembly complex (LUBAC) regulates NF-B activation by modifying proteins with linear (M1-linked) ubiquitination chains. Alt......

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