C-5 selective chlorination of 8-aminoquinoline amides using dichloromethane

Lin, XX; Zeng, CL; Liu, CK; Fang, Z; Guo, K

Liu, CK; Fang, Z (corresponding author), Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, 30 Puzhu Rd S, Nanjing 211816, Peoples R China.

ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (6): 1352

Abstract

An oxidant-free electrochemical regioselective chlorination of 8-aminoquinoline amides at ambient temperature in batch and continuous-flow was achieve......

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