N-6-methyladenine DNA Modification in Glioblastoma

Xie, Q; Wu, TP; Gimple, RC; Li, Z; Prager, BC; Wu, QL; Yu, Y; Wang, PC; Wang, YS; Gorkin, DU; Zhang, C; Dowiak, AV; Lin, KX; Zeng, C; Sui, YH; Kim, LJY; Miller, TE; Jiang, L; Lee, CH; Huang, Z; Fang, XG; Zhai, K; Mack, SC; Sander, M; Bao, SD; Kerstet

Rich, JN (reprint author), Univ Calif San Diego, Div Regenerat Med, Dept Med, La Jolla, CA 92037 USA.; Xiao, AZ (reprint author), Yale Sch Med, Dept Genet, New Haven, CT 06520 USA.; Xiao, AZ (reprint author), Yale Sch Med, Yale Stem Cell Ctr, New Haven, C

CELL, 2018; 175 (5): 1228

Abstract

Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the......

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