Human DNA polymerase theta harbors DNA end-trimming activity critical for DNA repair

Zahn, KE; Jensen, RB; Wood, RD; Doublie, S

Doublie, S (corresponding author), Univ Vermont, Dept Microbiol & Mol Genet, 89 Beaumont Ave, Burlington, VT 05405 USA.; Wood, RD (corresponding author), Univ Texas MD Anderson Canc Ctr, Dept Epigenet & Mol Carcinogenesis, Houston, TX 78957 USA.

MOLECULAR CELL, 2021; 81 (7): 1534

Abstract

Cancers with hereditary defects in homologous recombination rely on DNA polymerase theta (pol theta) for repair of DNA double-strand breaks. During en......

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