Both phosphorylation and phosphatase activity of PTEN are required to prevent replication fork progression during stress by inducing heterochromatin

Misra, S; Chowdhury, SG; Ghosh, G; Mukherjee, A; Karmakar, P

Karmakar, P (通讯作者),Jadavpur Univ, Dept Life Sci & Biotechnol, Kolkata, India.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 825 ():

Abstract

PTEN is a tumor suppressor protein frequently altered in various cancers. PTEN-null cells have a characteristic of rapid proliferation with an unstabl......

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