Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216

Cotton, TR; Cobbold, SA; Bernardini, JP; Richardson, LW; Wang, XYS; Lechtenberg, BC

Lechtenberg, BC (通讯作者)，Walter & Eliza Hall Inst Med Res, Ubiquitin Signalling Div, 1G Royal Parade, Parkville, Vic 3052, Australia.;Lechtenberg, BC (通讯作者)，Univ Melbourne, Dept Med Biol, Parkville, Vic 3010, Australia.

MOLECULAR CELL, 2022; 82 (3): 598

Abstract

An increasing number of genetic diseases are linked to deregulation of E3 ubiquitin ligases. Loss-of-function mutations in the RING-between-RING (RBR)......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索