Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease

Rayaprolu, S; Gao, TW; Xiao, HL; Ramesha, S; Weinstock, LD; Shah, J; Duong, DM; Dammer, EB; Webster, JA; Lah, JJ; Wood, LB; Betarbet, R; Levey, AI; Seyfried, NT; Rangaraju, S

Seyfried, NT; Rangaraju, S (corresponding author), Emory Univ, Dept Neurol, Sch Med, Whitehead Biomed Res Bldg,615 Michael St, Atlanta, GA 30322 USA.; Seyfried, NT (corresponding author), Emory Univ, Dept Biochem, Atlanta, GA 30322 USA.

MOLECULAR NEURODEGENERATION, 2020; 15 (1):

Abstract

Background Proteomic characterization of microglia provides the most proximate assessment of functionally relevant molecular mechanisms of neuroinflam......

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