Microphysiological Models for Mechanistic-Based Prediction of Idiosyncratic DILI

Stern, S; Wang, HB; Sadrieh, N

Wang, HB (通讯作者),Univ Maryland, Sch Pharm, Dept Pharmaceut Sci, 20 Penn St, Baltimore, MD 21201 USA.;Sadrieh, N (通讯作者),Ctr Drug Evaluat & Res, FDA, Off New Drugs, 10903 New Hampshire Ave, Silver Spring, MD 20993 USA.

CELLS, 2023; 12 (11):

Abstract

Drug-induced liver injury (DILI) is a major contributor to high attrition rates among candidate and market drugs and a key regulatory, industry, and g......

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