Synthesis and biological assay of erlotinib analogues and BSA-conjugated erlotinib analogue

Boobalan, R; Liu, KK; Chao, JI; Chen, CP

Chen, CP (reprint author), Natl Dong Hwa Univ, Dept Chem, Hualien 974, Taiwan.; Chen, CP (reprint author), Tzu Chi Univ Sci & Technol, Dept Nursing, Hualien 970, Taiwan.; Chao, JI (reprint author), Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu 30

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017; 27 (8): 1784

Abstract

A series of erlotinib analogues that have structural modification at 6,7-alkoxyl positions is efficiently synthesized. The in vitro anti-tumor activit......

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