Safety, anti-tumour activity, and pharmacokinetics of fixed- dose SHR-1210, an anti-PD-1 antibody in advanced solid tumours: a dose-escalation, phase 1 study

Mo, HN; Huang, J; Xu, JC; Chen, XL; Wu, DW; Qu, D; Wang, X; Lan, B; Wang, XY; Xu, JP; Zhang, HG; Chi, YHBL; Yang, Q; Xu, BH

Huang, J; Xu, BH (reprint author), Chinese Acad Med Sci, Canc Hosp, Natl Canc Ctr, Dept Med Oncol, Beijing 100021, Peoples R China.; Huang, J; Xu, BH (reprint author), Peking Union Med Coll, Beijing 100021, Peoples R China.

BRITISH JOURNAL OF CANCER, 2018; 119 (5): 538

Abstract

BACKGROUND: To assess the safety profile, pharmacokinetics, pharmacodynamics and preliminary antitumour activity of fixed-dose SHR-1210, a novel anti-......

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