Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C

Fakih, MG; Salvatore, L; Esaki, T; Modest, DP; Lopez-Bravo, DP; Taieb, J; Karamouzis, MV; Ruiz-Garcia, E; Kim, TW; Kuboki, Y; Meriggi, F; Cunningham, D; Yeh, KH; Chan, EMY; Chao, JS; Saportas, Y; Tran, Q; Cremolini, C; Pietrantonio, F

Fakih, MG (通讯作者),City Hope Comprehens Canc Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA.

NEW ENGLAND JOURNAL OF MEDICINE, 2023; 389 (23): 2125

Abstract

BackgroundKRAS G12C is a mutation that occurs in approximately 3 to 4% of patients with metastatic colorectal cancer. Monotherapy with KRAS G12C inhib......

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