Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer

Pu, XX; Zhang, R; Wang, L; Chen, YC; Xu, Y; Pataer, A; Meraz, IM; Zhang, XS; Wu, SH; Wu, L; Su, D; Mao, WM; Heymach, JV; Roth, JA; Swisher, SG; Fang, BL

Fang, BL (reprint author), Univ Texas MD Anderson Canc Ctr, Dept Thorac & Cardiovasc Surg, Houston, TX 77030 USA.

JOURNAL OF TRANSLATIONAL MEDICINE, 2018; 16 ():

Abstract

BackgroundBecause patient-derived xenografts (PDXs) are grown in immunodeficient mouse strains, PDXs are regarded as lacking an immune microenvironmen......

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