CD44+lung cancer stem cell-derived pericyte-like cells cause brain metastases through GPR124-enhanced trans-endothelial migration

Huang, Q; Liu, LP; Xiao, DK; Huang, Z; Wang, WJ; Zhai, K; Fang, XG; Kim, J; Liu, JM; Liang, WH; He, JX; Bao, SD

Bao, SD (通讯作者)，Cleveland Clin, Lerner Res Inst, Dept Canc Biol, Cleveland, OH 44195 USA.;He, JX (通讯作者)，Guangzhou Med Univ, Affiliated Hosp 1, Dept Thorac Surg, State Key Lab Resp Dis, Guangzhou 510120, Peoples R China.;He, JX (通讯作者)，Natl Clin Res Ctr Resp Dis, Guangzhou 510120, Peoples R China.;Bao, SD (通讯作者)，Cleveland Clin, Lerner Res Inst, Ctr Canc Stem Cell Res, Cleveland, OH 44195 USA.

CANCER CELL, 2023; 41 (9): 1621

Abstract

Brain metastasis of lung cancer causes high mortality, but the exact mechanisms underlying the metastasis remain unclear. Here we report that vascular......

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