Epigenetic silencing of ZCCHC10 by the lncRNA SNHG1 promotes progression and venetoclax resistance of acute myeloid leukemia

Zhou, H; Zhang, Q; Huang, W; He, CP; Zhou, C; Zhou, JL; Ning, YC

Zhou, JL (通讯作者),Hunan Normal Univ, State Key Lab Dev Biol Freshwater Fish, Changsha 410081, Hunan, Peoples R China.;Zhou, JL (通讯作者),Hunan Normal Univ, Coll Life Sci, Key Lab Prot Chem & Dev Biol, Minist Educ, Changsha 410081, Hunan, Peoples R China.;Ning, YC (通讯作者),Youjiang Med Univ Nationalities, Peoples Hosp Chongzuo, Chongzuo Key Lab Biomed Clin Transformat, Chongzuo 532200, Guangxi, Peoples R China.;Zhou, JL (通讯作者),Hunan Normal Univ, State Key Lab Dev Biol Freshwater Fish, 36 Lushan Rd, Changsha 410081, Hunan, Peoples R China.;Zhou, JL (通讯作者),Hunan Normal Univ, Coll Life Sci, Key Lab Prot Chem & Dev Biol, Minist Educ, 36 Lushan Rd, Changsha 410081, Hunan, Peoples R China.;Ning, YC (通讯作者),Youjiang Med Univ Nationalities, Chongzuo Key Lab Biomed Clin Transformat, Peoples Hosp Chongzuo, 6 East Longxiashan Rd, Chongzuo 532200, Peoples R China.

INTERNATIONAL JOURNAL OF ONCOLOGY, 2023; 62 (5):

Abstract

The gene encoding the tumor suppressor p53 is the most frequently mutated gene in cancers. However, p53 mutation is rare in acute myeloid leukemia (AM......

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