Covalent Modulators of the Vacuolar ATPase

Chen, YC; Backus, KM; Merkulova, M; Yang, C; Brown, D; Cravatt, BF; Zhang, C

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017; 139 (2): 639

Abstract

The vacuolar H+ ATPase (V-ATPase) is a complex multisubunit machine that regulates important cellular processes through controlling acidity of intrace......

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