High-speed parameter search of dynamic biological pathways from time-course transcriptomic profiles using high-level Petri net

Li, C; Qin, JL; Kuroyanagi, K; Lu, L; Nagasaki, M; Satoru, M

Li, C (corresponding author), Zhejiang Univ, Sch Med, Dept Human Genet, Hangzhou, Zhejiang, Peoples R China.; Li, C (corresponding author), Zhejiang Univ, Sch Med, Womens Hosp, Hangzhou, Zhejiang, Peoples R China.; Nagasaki, M (corresponding author), Kyoto Univ, Ctr Genom Med, Grad Sch Med, Sakyo Ku, Shogoinkawahara Cho, Kyoto, Kyoto, Japan.

BIOSYSTEMS, 2021; 201 ():

Abstract

Dynamic simulation promises a deeper understanding of complex molecular mechanisms of biological pathways. How to determine the reaction kinetic param......

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