Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor

He, YL; Dou, HX; Gao, DD; Wang, T; Zhang, MM; Wang, HY; Li, YX

Zhang, MM; Li, YX (reprint author), Fudan Univ, Sch Pharm, Shanghai 201203, Peoples R China.; Wang, HY (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY, 2019; 27 (19):

Abstract

Fatty acid binding protein 4 (FABP4) and fatty acid binding protein 5 (FABP5) are mainly expressed in adipocytes and/or macrophages and play essential......

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