Structure based classification for bile salt export pump (BSEP) inhibitors using comparative structural modeling of human BSEP

Jain, S; Grandits, M; Richter, L; Ecker, GF

Ecker, GF (reprint author), Univ Vienna, Dept Pharmaceut Chem, Althanstr 14, A-1090 Vienna, Austria.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2017; 31 (6): 507

Abstract

The bile salt export pump (BSEP) actively transports conjugated monovalent bile acids from the hepatocytes into the bile. This facilitates the formati......

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