Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation

Sun, ZZ; Li, YY; Qian, Y; Wu, MY; Huang, SM; Zhang, AH; Zhang, Y; Jia, ZJ

Zhang, Y; Jia, ZJ (reprint author), Nanjing Med Univ, Dept Nephrol, Childrens Hosp, Guangzhou Rd 72, Nanjing 210008, Jiangsu, Peoples R China.; Zhang, Y; Jia, ZJ (reprint author), Nanjing Med Univ, Jiangsu Key Lab Pediat, Nanjing 210029, Jiangsu, Peoples

CELL DEATH DISCOVERY, 2019; 5 ():

Abstract

Mesangial cell (MC) proliferation is one of the important pathological features of obesity-associated nephropathy with unknown etiology. Excessive MC ......

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